Nightfighter is a combat flight simulator. The player controls a fighter plane on a night mission, and his task is to take off, destroy the target, avoid enemy attack and return to base.
The history of this title is unclear. As far as we can tell it was never officially released during the original lifetime of the Odyssey 2, but was distributed by Retrogenesis in 2010. There are multiple Brazilian and European prototypes, of which this is one.
A little more information here: http://atariage.com/forums/topic/170608-nightfighter-new-odyssey-2-videopac-game/